Plaquex Therapy Information
Phosphatidylcholine (PTC) is a major
component of cell membrane and is localized preferentially in the
outer surface of the plasma membrane. It is also called lecithin.
However, the term lecithin has different meanings when used in
chemistry and biochemistry than when used commercially. Most
commercial products contain only 20% Phosphatidylcholine. PTC is 70%
phosphatidylcholine content. It is derived from soybeans.
"Phosphatidylcholine is important for normal
cellular membrane composition and repair. It is the major delivery
form of the essential nutrient choline. Choline itself is a
precursor in the synthesis of the neurotransmitter acetylcholine,
the methyl donor betaine and phospholipids, including
phosphatidylcholine and sphingomyelin among others.
Phosphatidylcholine is involved in the hepatic export of very low
The usefulness of the substance is
considerably greater in the intravenous state. The same results
cannot be obtained using
simply lecithin orally since only about 5 -10% of the substance is
utilized in the serum or fluid portion of the blood. With
intravenous(IV) infusion the absorption is considerably greater and
the correction, then, of any deficiency status is resolved sooner.
This is the reason that we, in medicine, use IVs because of the
absorbability of solutions is so much greater and the results so
PTC is used in this country for alleviation
of periorbital fat pads in this country. The Use of
Phosphatidylcholine for Correction of Lid Bulging Due to Prominent
Fat Pads(Dermatol Surg 2001:27:391-392)It is approved for this
purpose. PTC is not approved for other purposes but still quite
legal for medical use. It is considered an off label use.
We use the version of PTC available in this
country because of availability and legal issues. The only
difference in the solution that we use is the omission of
ATP(adenosine triphosphate).This is a relatively new procedure in
this country but has been used in Europe since about
The European version is available in this
country on a "compassionate need" basis only. This means that we can
only get the European version upon signed statement of
In Europe PTC is used for
atherosclerosis(angina pectoris, peripheral vascular disease such as
reduced blood flow to the legs, walking problems, stroke, carotid
obstruction etc) liver disease, kidney disease, possibly Alzheimer’s
disease and macular degeneration. There is a claim of reduction of
incidence of stroke or repeat stroke, reduction of angina pectoris
pain and frequency of attacks, lowering of LDL cholesterol,
increases HDL cholesterol, improvement of walking distance,
improvement of mental function and improved sexual function by the
European manufacturer. The effect of the procedure on your
individual cells will be determined by the damage and the severity
of damage to those cells.
Side effects are generally few and minimal in
nature. If the solution goes in too quickly we can see a drop of
blood pressure. Occasionally we see some diarrhea especially with
some patients who have had their gallbladders removed. Liver enzymes
such as the LDL and HDL are elevated. Usually the liver enzymes go
down quickly thereafter.
The procedure is done using the PTC solution
in a sterile bag of 5% dextrose and water. The amount of PTC per
treatment will gradually increase to a maximum dependant upon weight
and condition. The treatment is run as a series of usually twenty
treatments but your condition may require more treatment. PTC is run
in conjunction with chelation therapy usually on a 2:1 basis i.e.
two times PTC administration to 1x chelation. The PTC drip takes a
minimum of 90 minutes to run. The chelation takes twice that time.