Plaquex Therapy Information

Phosphatidylcholine (PTC) is a major component of cell membrane and is localized preferentially in the outer surface of the plasma membrane. It is also called lecithin. However, the term lecithin has different meanings when used in chemistry and biochemistry than when used commercially. Most commercial products contain only 20% Phosphatidylcholine. PTC is 70% phosphatidylcholine content. It is derived from soybeans.

"Phosphatidylcholine is important for normal cellular membrane composition and repair. It is the major delivery form of the essential nutrient choline. Choline itself is a precursor in the synthesis of the neurotransmitter acetylcholine, the methyl donor betaine and phospholipids, including phosphatidylcholine and sphingomyelin among others. Phosphatidylcholine is involved in the hepatic export of very low density lipoproteins."www.pdrhealth.com

The usefulness of the substance is considerably greater in the intravenous state. The same results cannot be obtained using simply lecithin orally since only about 5 -10% of the substance is utilized in the serum or fluid portion of the blood. With intravenous(IV) infusion the absorption is considerably greater and the correction, then, of any deficiency status is resolved sooner. This is the reason that we, in medicine, use IVs because of the absorbability of solutions is so much greater and the results so much quicker.

PTC is used in this country for alleviation of periorbital fat pads in this country. The Use of Phosphatidylcholine for Correction of Lid Bulging Due to Prominent Fat Pads(Dermatol Surg 2001:27:391-392)It is approved for this purpose. PTC is not approved for other purposes but still quite legal for medical use. It is considered an off label use.

We use the version of PTC available in this country because of availability and legal issues. The only difference in the solution that we use is the omission of ATP(adenosine triphosphate).This is a relatively new procedure in this country but has been used in Europe since about 1955.

The European version is available in this country on a "compassionate need" basis only. This means that we can only get the European version upon signed statement of "need".

In Europe PTC is used for atherosclerosis(angina pectoris, peripheral vascular disease such as reduced blood flow to the legs, walking problems, stroke, carotid obstruction etc) liver disease, kidney disease, possibly Alzheimer’s disease and macular degeneration. There is a claim of reduction of incidence of stroke or repeat stroke, reduction of angina pectoris pain and frequency of attacks, lowering of LDL cholesterol, increases HDL cholesterol, improvement of walking distance, improvement of mental function and improved sexual function by the European manufacturer. The effect of the procedure on your individual cells will be determined by the damage and the severity of damage to those cells.

Side effects are generally few and minimal in nature. If the solution goes in too quickly we can see a drop of blood pressure. Occasionally we see some diarrhea especially with some patients who have had their gallbladders removed. Liver enzymes such as the LDL and HDL are elevated. Usually the liver enzymes go down quickly thereafter.

The procedure is done using the PTC solution in a sterile bag of 5% dextrose and water. The amount of PTC per treatment will gradually increase to a maximum dependant upon weight and condition. The treatment is run as a series of usually twenty treatments but your condition may require more treatment. PTC is run in conjunction with chelation therapy usually on a 2:1 basis i.e. two times PTC administration to 1x chelation. The PTC drip takes a minimum of 90 minutes to run. The chelation takes twice that time.

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